12-Night Ho Chi Minh City to Siem Reap

APT Cruising · Mekong Serenity

Visit Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau and 11 more ports

Departure Ho Chi Minh City
Return Siem Reap
Duration 12 Nights

Itinerary

  1. Day 1
    Ho Chi Minh City Arrives 12:00 AM · Departs 12:00 AM
  2. Day 2
    Ho Chi Minh City Arrives 12:00 AM · Departs 12:00 AM
  3. Day 3
    Ho Chi Minh City Arrives 12:00 AM · Departs 12:00 AM
  4. Day 3
    My Tho Arrives 12:00 AM · Departs 12:00 AM
  5. Day 3
    Cai Be Arrives 12:00 AM · Departs 12:00 AM
  6. Day 4
    Cai Be Arrives 12:00 AM · Departs 12:00 AM
  7. Day 4
    Sa Dec Arrives 12:00 AM · Departs 12:00 AM
  8. Day 4
    Tan Chau Arrives 12:00 AM · Departs 12:00 AM
  9. Day 5
    Tan Chau Arrives 12:00 AM · Departs 12:00 AM
  10. Day 5
    Evergreen Island Arrives 12:00 AM · Departs 12:00 AM
  11. Day 5
    Border Crossing Arrives 12:00 AM · Departs 12:00 AM
  12. Day 5
    Phnom Penh Arrives 12:00 AM · Departs 12:00 AM
  13. Day 6
    Phnom Penh Arrives 12:00 AM · Departs 12:00 AM
  14. Day 7
    Phnom Penh Arrives 12:00 AM · Departs 12:00 AM
  15. Day 7
    Oudong Arrives 12:00 AM · Departs 12:00 AM
  16. Day 7
    Koh Chen Arrives 12:00 AM · Departs 12:00 AM
  17. Day 7
    Oknha Tey Arrives 12:00 AM · Departs 12:00 AM
  18. Day 8
    Oknha Tey Arrives 12:00 AM · Departs 12:00 AM
  19. Day 8
    Angkor Ban Arrives 12:00 AM · Departs 12:00 AM
  20. Day 8
    Wat Hanchey Arrives 12:00 AM · Departs 12:00 AM
  21. Day 9
    Wat Hanchey Arrives 12:00 AM · Departs 12:00 AM
  22. Day 9
    Kampong Cham Arrives 12:00 AM · Departs 12:00 AM
  23. Day 9
    Koh Pen Arrives 12:00 AM · Departs 12:00 AM
  24. Day 10
    Kampong Cham Arrives 12:00 AM · Departs 12:00 AM
  25. Day 10
    Siem Reap Arrives 12:00 AM · Departs 12:00 AM
  26. Day 11
    Siem Reap Arrives 12:00 AM · Departs 12:00 AM
  27. Day 12
    Siem Reap Arrives 12:00 AM · Departs 12:00 AM
  28. Day 13
    Siem Reap Arrives 12:00 AM · Departs 12:00 AM

Ports of Call

  • Ho Chi Minh City
  • My Tho
  • Cai Be
  • Sa Dec
  • Tan Chau
  • Evergreen Island
  • Border Crossing
  • Phnom Penh
  • Oudong
  • Koh Chen
  • Oknha Tey
  • Angkor Ban
  • Wat Hanchey
  • Kampong Cham
  • Koh Pen
  • Siem Reap

About This Cruise

12-night APT Cruising Mekong Serenity cruise from Ho Chi Minh City to My Tho, Cai Be, Sa Dec and Tan Chau Compare itinerary, pricing, cabins &…

Cruise Line APT Cruising
Ship Mekong Serenity

Frequently asked questions

What is included in the cruise fare?
Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.
How far in advance should I book this cruise?
For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on Mekong Serenity.
What documents do I need to board?
Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Ho Chi Minh City may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.
Can I change or cancel my booking?
Change and cancellation policies depend on APT Cruising's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.
What is a 12-night cruise like?
A 12-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from Mekong Serenity. Pack for both formal nights and casual deck days.